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Antiplatelet Therapy | Heart Attack Risk


BRILINTA is a prescription antiplatelet medication for people who have had a heart attack or severe chest pain (unstable angina) that happened because their heart was not getting enough oxygen.

BRILINTA is used with aspirin to lower your chance of having another serious problem with your heart or blood vessels, such as heart attack, stroke, or blood clots in your stent. These can be fatal.


Having a heart attack makes you more likely to have another one.

Select one of the tabs below to learn how BRILINTA can help after a heart attack and to see how BRILINTA works.


BRILINTA should be taken as prescribed twice a day, plus one 81-mg aspirin tablet once per day. Together, this can help keep your platelets from sticking together and forming new clots.


  • Take BRILINTA and aspirin exactly as instructed by your doctor
  • You should not take a dose of aspirin higher than 100 mg daily because it can affect how well BRILINTA works
  • Tell your doctor if you take other medicines that contain aspirin
  • Do not take new medicines that contain aspirin

BRILINTA is used to lower your chance of having another heart attack or dying from a heart attack or stroke, but BRILINTA (and similar drugs) can cause bleeding that can be serious and sometimes lead to death. Instances of serious bleeding, such as internal bleeding, may require blood transfusions or surgery. While you take BRILINTA, you may bruise and bleed more easily and be more likely to have nosebleeds. Bleeding will also take longer than usual to stop.

CALL YOUR DOCTOR RIGHT AWAY IF you have any signs or symptoms of bleeding while taking BRILINTA, including: severe, uncontrollable bleeding; pink, red, or brown urine; vomit that is bloody or looks like coffee grounds; red or black stool, or if you cough up blood or blood clots.

Here’s how the antiplatelet medicine, BRILINTA, works

Without BRILINTA plus aspirin, platelets can stick together and form a clot in a stent or in your artery. And that can cause another heart attack.

Image of artery without BRILINTA® (ticagrelor) plus aspirin

With BRILINTA plus aspirin, platelets are less likely to stick together and form a new and dangerous clot.

Image of artery with BRILINTA® (ticagrelor) plus aspirin

For illustrative purposes only.

Do not stop taking BRILINTA without talking to the doctor who prescribes it for you.

  • People who are treated with a stent, and stop taking BRILINTA too soon, have a higher risk of getting a blood clot in the stent, having a heart attack, or dying
  • If you stop BRILINTA because of bleeding, or for other reasons, your risk of a heart attack or stroke may increase
  • Tell all your doctors and dentists that you are taking BRILINTA
  • To decrease your risk of bleeding, your doctor may instruct you to stop taking BRILINTA 5 days before you have surgery
  • Your doctor should tell you when to start taking BRILINTA again, as soon as possible after surgery
Antiplatelet therapy and heart attack risk